GAD-Ab ELisa Test Kit

INTENDED USE

Detection Kit for Glutamic Acid Decarboxylase Antibody(GAD-Ab)(Enzyme-Linked ImmunoSorbent Assay , ELISA)GAD-Ab EIA kit is used in qualitative tests for Glutamic Acid Decarboxylase Antibody(GAD-Ab)in human serum

SUMMARY AND CLINICAL SIGNIFICANCE

Glutamate decarboxylase (GAD) is a rate-limiting enzyme that converts glutamate into an inhibitory neurotransmitter gamma-aminobutyric acid (GABA), GAD exists in islet β cells, and is also synthesized and secreted by GABA. Glutamate decarboxylase antibody (GADA) is an immune marker for the early stage of type 1 diabetes mellitus and is also used as a therapeutic indicator for the treatment of type 1 diabetes mellitus. The prevalence of GADA in patients with type 1 diabetes mellitus with Graves disease was significantly higher than that in patients with type 1 diabetes without Graves disease. GAD levels in patients with Graves were significantly higher, and the incidence of GADA in non-diabetic patients did not always predict type 1 diabetes.

PRINCIPLE

GAD-Ab EIA Kit will advance the recombinant human Glutamic Acid Decarboxylase was coated on the reaction plate, is used to capture the GAD-Ab in the sample, washing out extraneous material, then adding horseradish peroxidase (HRP) labeled mouse anti human IgG antibody. Finally, the formation of solid phase labeled anti-human

IgG complex, plus TMB color system after the role of color, the sample can be detected in human serum insulin antibody in the presence of the determination.

PRECAUTION FOR USERS

• Handling should preclude any pipetting by mouth.
• Use only pipettes with disposable tips for each specimen.
• Do not mix materials from different master lots. Do not use kit components beyond the expiration date. All materials should be brought to room temperature before use.

GAD-Ab ELISA Immunoassay Detection Kit

Glutamic Acid Decarboxylase Antibody Kit

ELISA Immunoassay Detection Kit Glutamic Acid Decarboxylase Antibody GAD-Ab ELisa Test Kit Images